Pre-ribosomes on the road from the nucleolus to the cytoplasm.

  title={Pre-ribosomes on the road from the nucleolus to the cytoplasm.},
  author={Herbert Tschochner and Ed Hurt},
  journal={Trends in cell biology},
  volume={13 5},
Eukaryotic ribosomes are assembled in the nucleolus before export to the cytoplasm. Ribosome formation is a highly dynamic and coordinated multistep process, which requires synthesis, processing and modification of pre-rRNAs, assembly with ribosomal proteins and transient interaction of numerous non-ribosomal factors with the evolving pre-ribosomal particles. In the past two years, exciting insights into the sequential events occurring during pre-ribosome formation have been obtained, thanks… CONTINUE READING
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