Pre-operative risk assessment and risk reduction before surgery.

  title={Pre-operative risk assessment and risk reduction before surgery.},
  author={Don Poldermans and Sanne Elisabeth Hoeks and Harm H. H. Feringa},
  journal={Journal of the American College of Cardiology},
  volume={51 20},
Perioperative myocardial infarctions are the predominant cause of morbidity and mortality in patients undergoing noncardiac surgery. The pathophysiology of perioperative myocardial infarction is complex. Prolonged myocardial ischemia due to the stress of surgery in the presence of a hemodynamically significant coronary lesion, leading to subendocardial ischemia, and acute coronary artery occlusion after plaque rupture and thrombus formation contribute equally to these devastating events… CONTINUE READING
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