Pre-clinical toxicology of garcinielliptone FC, a tautomeric pair of polyprenylated benzophenone, isolated from Platonia insignis Mart seeds.

@article{daSilva2016PreclinicalTO,
  title={Pre-clinical toxicology of garcinielliptone FC, a tautomeric pair of polyprenylated benzophenone, isolated from Platonia insignis Mart seeds.},
  author={Ana Paula dos Santos C L da Silva and George Laylson da Silva Oliveira and Shirlene Ces{\'a}rio Medeiros and Allyson Martins Lopes Sousa and Luciano da Silva Lopes and Jorge Mauricio David and Joaquim Soares da Costa J{\'u}nior and Rivelilson Mendes de Freitas},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2016},
  volume={23 5},
  pages={
          477-82
        }
}
BACKGROUND Garcinielliptone FC (GFC) is a tautomeric pair of polyprenylated benzophenone, which has proven to have antiepileptic, cytotoxic and antioxidant activity. PURPOSE The aim of this study was to investigate the biochemical, hematological and pathological effects of the acute toxicity study as well as to assess the locomotor activity and motor coordination in mice treated with GFC. METHODS Swiss mice of both sexes weighing 25-30 g divided into three separate groups of five animals… Expand
13 Citations
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