Corpus ID: 24369375

Pre-clinical toxicity & immunobiological evaluation of DNA rabies vaccine & combination rabies vaccine in rhesus monkeys (Macaca mulatta)

@article{Kumar2013PreclinicalT,
  title={Pre-clinical toxicity & immunobiological evaluation of DNA rabies vaccine & combination rabies vaccine in rhesus monkeys (Macaca mulatta)},
  author={B. D. Kumar and P. U. Kumar and T. P. Krishna and S. Kalyanasundaram and P. Suresh and V. Jagadeesan and S. Hariharan and A. Naidu and K. Krishnaswamy and P. N. Rangarajan and V. Srinivasan and G. N. Reddy and B. Sesikeran},
  journal={The Indian Journal of Medical Research},
  year={2013},
  volume={137},
  pages={1072 - 1088}
}

B. D. Kumar, P. U. Kumar, +10 authors B. Sesikeran

Published 2013

Biology, Medicine

The Indian Journal of Medical Research

Background & objectives: Pre-clinical toxicology evaluation of biotechnology products is a challenge to the toxicologist. The present investigation is an attempt to evaluate the safety profile of the first indigenously developed recombinant DNA anti-rabies vaccine [DRV (100 μg)] and combination rabies vaccine [CRV (100 μg DRV and 1.25 IU of cell culture-derived inactivated rabies virus vaccine)], which are intended for clinical use by intramuscular route in Rhesus monkeys. Methods: As per the… CONTINUE READING

View on PubMed

icmr.nic.in

Save to Library

Create Alert

Cite

Launch Research Feed