Pre- and postnatal exposure to low-dose diesel exhaust impairs murine spermatogenesis.

  title={Pre- and postnatal exposure to low-dose diesel exhaust impairs murine spermatogenesis.},
  author={Miyoko Kubo-Irie and Shigeru Oshio and Yuichiro Niwata and Aki Ishihara and Isamu Sugawara and Kazuki Takeda},
  journal={Inhalation toxicology},
  volume={23 13},
We investigated whether pre- and postnatal low-dose exposure to diesel exhaust (DE) affects male reproductive function in mice. The DE concentration is less than that indicated as the environmental quality standard for suspended particulate matter (SPM) in Japan. ICR mice were exposed prenatally to low-dose diesel exhaust (0.17 mg of DE particles/m³) through the airway for 8 h/day in an exposure chamber from gestational day 2 until the examination. In the DE-exposed groups, normal sperm… CONTINUE READING
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