Pre- and postjunctional supersensitivity of the mesenteric artery preparation from normotensive and hypertensive rats

@article{Haeusler1970PreAP,
  title={Pre- and postjunctional supersensitivity of the mesenteric artery preparation from normotensive and hypertensive rats},
  author={Guenther Haeusler and Willy E. Haefely},
  journal={Naunyn-Schmiedebergs Archiv f{\"u}r Pharmakologie},
  year={1970},
  volume={266},
  pages={18-33}
}
Vasoconstrictor responses to noradrenaline, KCl and periarterial nerve stimulation were studied in isolated mesenteric artery preparations from normotensive, genetically hypertensive and renal hypertensive rats. Innormotensive rats sympathetic denervation or cocaine produced a shift of the dose-response curve for noradrenaline to the left by a factor of approximately 3 but did not alter the dose-response curve for KCl; in denervated arteries cocaine did not affect the dose-response curve for… CONTINUE READING
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