Pre- and post-mitotic events contribute to the progressive acquisition of area-specific connectional fate in the neocortex.

@article{Polleux2001PreAP,
  title={Pre- and post-mitotic events contribute to the progressive acquisition of area-specific connectional fate in the neocortex.},
  author={Franck Polleux and C. Dehay and Andr{\'e} Goffinet and Henry Kennedy},
  journal={Cerebral cortex},
  year={2001},
  volume={11 11},
  pages={1027-39}
}
The adult primary motor cortex (area 6) is characterized by a stronger projection to the spinal cord than the primary somatosensory cortex (area 3). Here we have explored the progressive and regressive phenomena that determine these areal differences in the number of corticospinal neurons (CSNs). CSNs were birthdated with [(3)H]thymidine and subsequently retrogradely labeled from the spinal cord. The time window of CSN production is identical in both areas. The probability that a cohort of… CONTINUE READING

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fate specification : a view from the nervous system

  • RT Ferri, P Levitt
  • 1993
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