Pre-Columbian treponemal disease from 14th century AD Safed, Israel, and implications for the medieval eastern Mediterranean.
@article{Mitchell2003PreColumbianTD,
title={Pre-Columbian treponemal disease from 14th century AD Safed, Israel, and implications for the medieval eastern Mediterranean.},
author={Piers D. Mitchell},
journal={American journal of physical anthropology},
year={2003},
volume={121 2},
pages={
117-24
}
}In 1912, 68 medieval crania were excavated from a cave at Safed in the eastern Mediterranean and brought to the United Kingdom. It is only recently that these skulls have been studied for evidence of disease. One adult individual demonstrates multiple lesions of the cranial vault, compatible with treponematosis. Radiocarbon dating suggests the year of death to be between 1290-1420 AD. This range equates to the mamluk period, just after the crusades. This is the oldest dated case of…
27 Citations
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References
SHOWING 1-10 OF 32 REFERENCES
Pre-Columbian treponematosis in medieval Britain
- Medicine
- 1991
Evidence is presented for the presence of treponemal disease in medieval Norwich prior to AD 1492 and differential diagnosis and geographical situation suggest that this skeleton displays evidence of syphillis.
Pre‐Columbian congenital syphilis from the late antiquity in France
- Medicine
- 1992
This case consists of an argument against the epidemiological theories about the migration of Treponema pallidum from the New World back to the Old World starting at the end of the 15th century.
Two probable cases of treponemal disease of Medieval date from England.
- MedicineAmerican journal of physical anthropology
- 2003
Two British Medieval skeletons are described. Paleopathological examination suggests that treponemal disease was present in each case. Radiocarbon dating indicates that one is firmly pre-Columbian,…
Treponematosis in Pre‐Spanish Western Micronesia
- Medicine
- 1996
On a sample of 486 individuals, it is found 17–27% of adults and 10 per cent of children to have skeletal yaws, suggesting treponema was present at least as early as the ninth centuryAD.
The palaeopathology of leprosy in Britain: a review.
- HistoryWorld archaeology
- 1989
The history of leprosy reached Britain and rose to a peak between the eleventh and thirteenth centuries and declined rapidly by the sixteenth century, when it had declined rapidly.
An introduction to diagnostic criteria of syphilis, treponarid and Yaws (treponematoses) in dry bones, and some implications
- MedicineVirchows Archiv A
- 2004
Diagnostic criteria of syphilis and some other diseases are proposed from a study of 424 crania and calvariae and 250 long bones in 22 medical museums in Europe, finding the sequence of changes of Virchow's caries sicca, and in long bones nodes/expansions with superficial cavitation are sound indicators of Syphilis.
Radiocarbon dates and the history of treponematoses in man.
- BiologyJournal of archaeological science
- 1975
Identification of Treponema pallidum subspecies pallidum in a 200-year-old skeletal specimen.
- BiologyThe Journal of infectious diseases
- 1999
Molecular determination of historical disease states by using skeletal material can significantly enhance the understanding of the pathology and spread of infectious diseases.
Historical approach to the terminology of syphilis.
- MedicineArchives of dermatology
- 1961
The difficulty of identifying syphilis prior to about 1500 has so discouraged some students of the subject as to persuade them that it could not have been present in the Old World before the return of Columbus from the New in 1493.
Pathology of bedouin skeletal remains from two sites in Israel.
- MedicineAmerican journal of physical anthropology
- 1976
Frequency of pathology and of some anomalies in skeletons of Bedouin living about 200 BP, uncovered in the Israeli Negev, is considered in relation to particular bone, sex, age-group, and kinds of…




