Pre-Clinical Pharmacokinetics of Sufentanil-2-Hydroxypropyl-Β-Cyclodextrin Inclusion Complex

@inproceedings{Calafatti2017PreClinicalPO,
  title={Pre-Clinical Pharmacokinetics of Sufentanil-2-Hydroxypropyl-Β-Cyclodextrin Inclusion Complex},
  author={Silvana Aparecida Calafatti and Marcelo de Macedo and Juliana Zampoli Boava Papini and Edvaldo and Coelho and C{\'i}ntia Maria Saia Cereda and Jos{\'e} Pedrazzoli J{\'u}nior and Eneida de Paula and Daniele L Ribeiro and De Ara{\'u}jo and Giovana Radomille Tofoli},
  year={2017}
}
This study evaluated the pre-clinical pharmacokinetics induced by sufentanil-2-hydroxypropyl-β-cyclodextrin inclusion complex (SUFHP-β-CD) in comparison with its aqueous formulation (SUF) after intramuscular injection in rabbits and pigs. New Zealand White rabbits and Landrace pigs were divided in two groups (n = 5/6) and treated by intramuscular route with… CONTINUE READING