Prdm6 Is Essential for Cardiovascular Development In Vivo

Abstract

Members of the PRDM protein family have been shown to play important roles during embryonic development. Previous in vitro and in situ analyses indicated a function of Prdm6 in cells of the vascular system. To reveal physiological functions of Prdm6, we generated conditional Prdm6-deficient mice. Complete deletion of Prdm6 results in embryonic lethality due… (More)
DOI: 10.1371/journal.pone.0081833

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