Prdm 12 specifies V 1 interneurons through cross-repressive interactions with Dbx 1 and Nkx 6 genes in Xenopus

@inproceedings{Thlie2015Prdm1S,
  title={Prdm 12 specifies V 1 interneurons through cross-repressive interactions with Dbx 1 and Nkx 6 genes in Xenopus},
  author={Aurore Th{\'e}lie and Simon Desiderio and Julie Hanotel and Ian K Quigley and Benoit Van Driessche and Anthony Rodari and Mark D. Borromeo and Sadia Kricha and François Lahaye and Jenifer C Croce and Gustavo Cerda-Moya and o Fernandez and Barbara Bolle and Katharine E Lewis and Maike Sander and Alessandra Pierani and Michael Schubert and Jane E. Johnson and Christopher R. Kintner and Tomas Pieler and Carine Van Lint and Kristine A. Henningfeld and Eric J Bellefroid and Claude Van Campenhout},
  year={2015}
}
V1 interneurons are inhibitory neurons that play an essential role in vertebrate locomotion. The molecular mechanisms underlying their genesis remain, however, largely undefined. Here, we show that the transcription factor Prdm12 is selectively expressed in p1 progenitors of the hindbrain and spinal cord in the frog embryo, and that a similar restricted expression profile is observed in the nerve cord of other vertebrates as well as of the cephalochordate amphioxus. Using frog, chick and mice… CONTINUE READING
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