Pravastatin therapy in hyperlipidemia: effects on thrombus formation and the systemic hemostatic profile.

@article{Dangas1999PravastatinTI,
  title={Pravastatin therapy in hyperlipidemia: effects on thrombus formation and the systemic hemostatic profile.},
  author={George D Dangas and Juan Jose Badimon and Donald Angehr Smith and Abraham Unger and Daniel H. Levine and John H Shao and Perwaiz M Meraj and C M Fier and John T. Fallon and John A Ambrose},
  journal={Journal of the American College of Cardiology},
  year={1999},
  volume={33 5},
  pages={1294-304}
}
OBJECTIVES The study sought to determine the effects of lipid-lowering with pravastatin on the systemic fibrinolytic profile and on thrombus formation under dynamic flow conditions. BACKGROUND Lowering cholesterol (C) decreases clinical events in coronary artery disease (CAD) patients, but an analysis of the effects of lipid-lowering on the entire hemostatic and thrombotic profile has not been conducted. METHODS We prospectively studied 93 stable patients with untreated low-density… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 54 references

Lipid-lowering therapy reduces blood thrombogenicity in hypercholesterolemic patients: effect of simvastatin

  • U Rauch, JJ Badimon, DA Vorchheimer
  • J Am Coll Cardiol 1998;31 Suppl A:194A
  • 1999
1 Excerpt

Coronary Prevention Study Group. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation 1998;97:1440–5

  • West of Scotland
  • 1998
1 Excerpt

Influ - ence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study ( WOSCOPS )

  • FM Sacks, LA Moye, BR Davis
  • Circulation
  • 1998

Characterization of the relative thrombogenicity of atherosclerotic plaque components: implication for consequences of plaque rupture

  • A Femandez-Ortiz, JJ Badimon, E Falk
  • J Am Coll Cardiol
  • 1996
1 Excerpt

Comparative effect of pravastatin and simvastatin on platelet thrombus formation in hypercholesterolemic coronary patients

  • L Lacoste, Lam JYT
  • J Am Coll Cardiol
  • 1996
1 Excerpt

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