Pravastatin and cognitive function in the elderly. Results of the PROSPER study

@article{Trompet2009PravastatinAC,
  title={Pravastatin and cognitive function in the elderly. Results of the PROSPER study},
  author={Stella Trompet and Peter Van de Vliet and Anton J. M. de Craen and Jelle Jolles and Brendan M. Buckley and Michael B. Murphy and Ian Ford Ford and Peter W Macfarlane and Naveed 4 Sattar and Chris J. Packard and David Stott and Jim Shepherd and Eduard L. E. M. Bollen and Gerard Jan Blauw and J Wouter Jukema and Rudi G. J. Westendorp},
  journal={Journal of Neurology},
  year={2009},
  volume={257},
  pages={85-90}
}
Observational studies have given conflicting results about the effect of statins in preventing dementia and cognitive decline. Moreover, observational studies are subject to prescription bias, making it hard to draw definite conclusions from them. Randomized controlled trials are therefore the preferred study design to investigate the association between statins and cognition. Here we present detailed cognitive outcomes from the randomized placebo-controlled PROspective Study of Pravastatin in… CONTINUE READING