Practice parameters for determining brain death in adults

  title={Practice parameters for determining brain death in adults},
  author={Lippincott Williams Wilkins},
  pages={1012 - 1014}
Overview. Brain death is defined as the irreversible loss of function of the brain, including the brainstem. Brain death from primary neurologic disease usually is caused by severe head injury or aneurysmal subarachnoid hemorrhage. In medical and surgical intensive care units, however, hypoxic-ischemic brain insults and fulminant hepatic failure may result in irreversible loss of brain function. In large referral hospitals, neurologists make the diagnosis of brain death 25 to 30 times a year. 
Brain Death Evaluation and Determination
This chapter outlines the basic diagnosis of brain death as described by the American Academy of Neurology guidelines, which includes the cardinal findings of brainDeath, as well as confirmatory tests that can be used as ancillary evidence of braindeath.
Brain death and withdrawal of support.
Brain Death Determination
Bedside clinicians are intended to give bedside clinicians an overview of definition, the causes and pitfalls of misdiagnosing brain death, and a focus on the specifics of the brain death determination process.
Determination of and Difficulties with Brain Death
The purpose of this chapter is to provide a general overview of brain death considerations and tools available to the clinician.
The definition and determination of brain death
Conventional angiography is the most sensitive technique, but relatively expensive, and because of potential side-effects not allowed for diagnosis in all countries, Electroencephalography and transcranial Doppler ultrasonography are alternative methods.
Brain Death and Management of the Potential Donor
The identification of patients progressing to brain death, as well as those with an established diagnosis, must be managed in the best possible way in an attempt to enable, if authorized, organs of good quality.
Brain death criteria. The neurological determination of death.
  • M. Jan
  • Medicine, Psychology
  • 2008
The objective of this article is to present updated guidelines for the process of brain death determination, and suggest tests of brain blood flow are preferred in the setting of hypothermia, metabolic, or drug confounders.
Transcranial Doppler as an Confirmatory Test in Brain Death
Bedside transcranial Doppler is presented along with the criteria and its value in brain death confirmation, and the use of neurosonologic tests that show a high resistance pattern in hemodynamics in parallel with the increase of intracranial pressure, eventually leading to cerebral circulatory arrest.
Neuropathology of brain death in the modern transplant era
No distinctive neuropathologic features were apparent in the series of patients with brain death, but mild changes were present in a third of the examined hemispheres and in half of the brainstems.