Practice parameter: Management of dementia (an evidence-based review)

@article{Doody2001PracticePM,
  title={Practice parameter: Management of dementia (an evidence-based review)},
  author={Rachelle Doody and Justin Stevens and C Beck and Richard Dubinsky and Jeffery A. Kaye and Lisa P. Gwyther and Richard C. Mohs and Leon Thal and Peter Whitehouse and Steven T. DeKosky and Jefferey Cummings},
  journal={Neurology},
  year={2001},
  volume={56},
  pages={1154 - 1166}
}
Objective: To define and investigate key issues in the management of dementia and to make literature-based treatment recommendations. Methods: The authors searched the literature for four clinical questions: 1) Does pharmacotherapy for cognitive symptoms improve outcomes in patients with dementia? 2) Does pharmacotherapy for noncognitive symptoms improve outcomes in patients with dementia? 3) Do educational interventions improve outcomes in patients and/or caregivers? 4) Do other… 
Practice parameter: Management of dementia (an evidence-based review)
TLDR
The uncorrected, first-pass data analysis revealed no significant beneficial effect of vitamin E and there were no significant effects on cognitive measures in the study, certainly raising the possibility that any poorly defined effect of Vitamin E on the outcome measure may have nothing specifically to do with AD.
Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence.
TLDR
Of the agents reviewed, the atypical antipsychotics risperidone and olanzapine currently have the best evidence for efficacy, however, the effects are modest and further complicated by an increased risk of stroke.
Evidence-Based Nonpharmacological Practices to Address Behavioral and Psychological Symptoms of Dementia
TLDR
Nonpharmacological practices to address behavioral and psychological symptoms of dementia (BPSDs) and provide evidence-based recommendations for dementia care especially useful for potential adopters are identified and critiqued.
Access to diagnostic evaluation and treatment for dementia in Europe
TLDR
A multidisciplinary approach based on close collaboration between GPs and specialised memory clinics may be the ideal model for early accurate diagnosis and subsequently early pharmacological and psychosocial interventions.
Management of the behavioral and psychological symptoms of dementia
TLDR
Clinicians should discuss the potential risks and benefits of treatment with patients and their surrogate decision makers, and must ensure a balance between side effects and tolerability compared with clinical benefit and QOL.
Behavioural symptoms of dementia in residential settings: A selective review of non-pharmacological interventions
  • S. Turner
  • Psychology, Medicine
    Aging & mental health
  • 2005
TLDR
A structured decision-making process for selection of interventions is proposed, in which the limited available evidence can be drawn together to provide a basis for targeting clinical resources while the research evidence is strengthened.
Dementia and Comorbidities: An Overview of Diagnosis and Management
TLDR
The diagnosis and management of common types of dementia and comorbidities are reviewed, including delirium, which is treated primarily by addressing underlying medical disorders, but antipsychotics can be useful for symptom management and patient comfort.
A systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia.
TLDR
The evidence for clinical effectiveness and cost-effectiveness of non-pharmacological interventions for reducing agitation in dementia, considering dementia severity, the setting, the person with whom the intervention is implemented, whether the effects are immediate or longer term, is reviewed.
Evaluation of the Diagnosis and Management of Cognitive Impairment in Long‐term Care
TLDR
Although depressive and behavioral symptoms were frequently diagnosed and interventions initiated, the diagnosis and management of cognitive impairment were often imprecise or absent, so that greater numbers of patients can benefit from recommended strategies.
Canadian Outcomes Study in Dementia: Study Methods and Patient Characteristics
TLDR
The Canadian Outcomes Study in Dementia is already generating valuable information about treatment patterns, outcomes, and resource use in Canadian patients with dementia, and it will be possible to build robust models on treatment effectiveness and costs of care.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 371 REFERENCES
Effects of respite care on patients with dementia and their caregivers.
  • A. Flint
  • Medicine, Psychology
    International psychogeriatrics
  • 1995
TLDR
There was little evidence that formal respite care has a significant effect on caregivers' burden, psychiatric status, or physical health; or on patients' cognition, function, physical health, or rate of institutionalization.
A nursing intervention to decrease depression in family caregivers of persons with dementia.
Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group.
TLDR
Results show that 1 mg/day of risperidone is an appropriate dose for most elderly patients with dementia, and significantly improved symptoms of psychosis and aggressive behavior in patients with severe dementia.
Therapeutic efficacy of pyritinol in patients with senile dementia of the Alzheimer type (SDAT) and multi-infarct dementia (MID).
TLDR
It can be accepted that the therapeutic effect of pyritinol is superior to placebo in patients with mild to moderate dementia of both degenerative and vascular etiology.
Depression in patients referred to a dementia clinic. A three-year prospective study.
TLDR
Depressed elderly patients with any of the following are at high risk to develop dementia: evidence of cerebrovascular, extrapyramidal, or spinocerebellar disease; a modified Hachinski ischemic score of 4 or greater; a Mental Status Questionnaire score under 8; a dementia behavior score of 7 or higher; or confusion on low doses of tricyclic antidepressants.
Therapeutic efficacy of vincamine in dementia.
TLDR
It can be accepted that the therapeutic effect of vincamine is superior to placebo in patients with mild to moderate dementia of degenerative and vascular etiologies.
Efficacy of a sensory integration program on behaviors of inpatients with dementia.
  • L. Robichaud, R. Hébert, J. Desrosiers
  • Psychology, Medicine
    The American journal of occupational therapy : official publication of the American Occupational Therapy Association
  • 1994
TLDR
Before this type of program is labeled inefficacious, other studies are necessary to determine whether modifying the frequency of sessions, the number of subjects, and the measuring instruments would lead to similar results.
Evaluation of dementia: A systematic study of the usefulness of the American Academy of Neurology's Practice Parameters
TLDR
Although imperfect, the Practice Parameters represent a first step toward improving the cost effectiveness of the dementia work-up, although at a significant difference in cost.
The course of geriatric depression with "reversible dementia": a controlled study.
TLDR
It is suggested that geriatric depression with reversible dementia is a clinical entity that includes a group of patients with early-stage dementing disorders and is an indication for a thorough diagnostic workup and frequent follow-ups in order to identify treatable neurological disorders.
Management of problematic behavioral symptoms associated with dementia: A cognitive developmental approach
TLDR
Results of the study indicate that using behavioral and environmental interventions based on Piaget levels of cognitive development may be an effective method of managing problematic behavioral symptoms and decreasing the use of psychotropic medications in institutionalized ADRD patients.
...
1
2
3
4
5
...