Practice Bulletin No. 143: Medical Management of First-Trimester Abortion

  title={Practice Bulletin No. 143: Medical Management of First-Trimester Abortion},
  journal={Obstetrics \& Gynecology},
  • Published 1 March 2014
  • Medicine
  • Obstetrics & Gynecology
Over the past three decades, medical methods of abortion have been developed throughout the world and are now a standard method of providing abortion care in the United States. Medical abortion, which involves the use of medications rather than a surgical procedure to induce an abortion, is an option for women who wish to terminate a first-trimester pregnancy. Although the method is most commonly used up to 63 days of gestation (calculated from the first day of the last menstrual period), the… 
56 Citations

Medication to Manage Abortion and Miscarriage

Clinical considerations and resources for integrating mifepristone and misoprostol into clinical practice are discussed, and clinicians can expand access to time-sensitive health services for vulnerable populations.

First trimester termination of pregnancy.

  • M. LuiP. Ho
  • Medicine
    Best practice & research. Clinical obstetrics & gynaecology
  • 2019

Comparison between Medical and Surgical Treatment of Incomplete First Trimester Abortion

Misoprostol is found to be as effective as surgical treatment in the treatment of incomplete miscarriage, at a single dose of 200 mcg, with complete evacuation of uterus in most women, and the side effects can be tolerated by all patients.

Self-managed abortion.

The safest environment for self-managed abortion (SMA) is one where accurate information is available, medical care is accessible when needed, and all methods of abortion remain legal.

Serum β-hCG concentration is a predictive factor for successful early medical abortion with vaginal misoprostol within 24 hours

Misoprostol monotherapy has a high success rate for first trimester abortion and women with serum β-hCG less than 40,000 mIU/mL are likely to achieve a successful abortion within 24 hours after intravaginal administration of misoprostols.

Comparison of Using Misoprostol with or without Letrozole in Abortion Induction: A Placebo-Controlled Clinical Trial

A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion and Evaluation of effect of let rozole prior to misop frostol in comparison with misOProstol alone in success rate of induced abortion are studied.

Medication abortion: Potential for improved patient access through pharmacies.

Abortion Surveillance — United States, 2015

In 2015, all three measures reached their lowest level for the entire period of analysis, and women in their 20s accounted for the majority of abortions and had the highest abortion rates; women aged ≥30 years accounted for a smaller percentage of pregnancies and had lower abortion rates.