Practice-Based Evidence Study Design for Comparative Effectiveness Research

@article{Horn2007PracticeBasedES,
  title={Practice-Based Evidence Study Design for Comparative Effectiveness Research},
  author={Susan D. Horn and Julie Gassaway},
  journal={Medical Care},
  year={2007},
  volume={45},
  pages={S50-S57}
}
Objectives:To describe a new, rigorous, comprehensive practice-based evidence for clinical practice improvement (PBE-CPI) study methodology, and compare its features, advantages, and disadvantages to those of randomized controlled trials and sophisticated statistical methods for comparative effectiveness research. Research Design:PBE-CPI incorporates natural variation within data from routine clinical practice to determine what works, for whom, when, and at what cost. It uses the knowledge of… 
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250 Citations
Highly Influential Citations
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Methods Citations
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250 Citations

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Citation Type

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Conference papers covered numerous points about ways to structure both interventional and database-oriented studies, particularly those concerned with adverse drug events, to avoid bias in those studies, and to apply advanced statistical tools to exploit the information from these studies to their fullest.
Comparative effectiveness and implementation research: Directions for Neurology
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Neuroscientists and neuroscientists should understand the scope and objectives of comparative effectiveness and implementation research, their range of methodological approaches, and existing research resources relevant to research for neurological conditions, to close the well‐documented evidence‐to‐practice gap.
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This review sought to present PBR studies as alternative designs to answer clinical questions, but not replacing randomized clinical trials.
A Tipping Point for Measurement-Based Care.
OBJECTIVE Measurement-based care involves the systematic administration of symptom rating scales and use of the results to drive clinical decision making at the level of the individual patient. This…
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