Practice-Based Evidence: Profiling the Safety of Cilostazol by Text-Mining of Clinical Notes

@inproceedings{Leeper2013PracticeBasedEP,
  title={Practice-Based Evidence: Profiling the Safety of Cilostazol by Text-Mining of Clinical Notes},
  author={Nicholas J. Leeper and Anna Bauer-Mehren and Srinivasan V. Iyer and Paea LePendu and Cliff Olson and Nigam Haresh Shah},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Peripheral arterial disease (PAD) is a growing problem with few available therapies. Cilostazol is the only FDA-approved medication with a class I indication for intermittent claudication, but carries a black box warning due to concerns for increased cardiovascular mortality. To assess the validity of this black box warning, we employed a novel text-analytics pipeline to quantify the adverse events associated with Cilostazol use in a clinical setting, including patients with… CONTINUE READING
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