Practical utility of the D-dimer assay for excluding thromboembolism in severely injured trauma patients.

@article{Owings2001PracticalUO,
  title={Practical utility of the D-dimer assay for excluding thromboembolism in severely injured trauma patients.},
  author={John T. Owings and Robert C Gosselin and John G. Anderson and Felix D. Battistella and Micaela Bagley and Edward C. Larkin},
  journal={The Journal of trauma},
  year={2001},
  volume={51 3},
  pages={425-9; discussion 429-30}
}
BACKGROUND We have advocated the use of a D-dimer assay to exclude the diagnosis of pulmonary embolism (PE) and deep venous thrombosis (DVT) in surgical and trauma patients suspected of having these diagnoses. Injury is known to increase D-dimer levels independent of thromboembolism. The purpose of this study was to assess the period after injury over which the D-dimer assay remains positive because of injury exclusive of thromboembolism. METHODS We prospectively sampled the plasma of… CONTINUE READING