Practical management of coagulopathy associated with warfarin
@article{Garcia2010PracticalMO, title={Practical management of coagulopathy associated with warfarin}, author={David A. Garcia and Mark Andrew Crowther and Walter Ageno}, journal={BMJ : British Medical Journal}, year={2010}, volume={340} }
When choosing a management strategy for a patient who is being treated with a vitamin K antagonist and presents with an INR outside the therapeutic range, consider the risk of both bleeding and thrombosis
20 Citations
Treatment of warfarin-associated coagulopathy with vitamin K
- MedicineExpert review of hematology
- 2011
Despite development of new oral anticoagulant therapy compounds, warfarin will probably retain a prominent role in thromboembolism management for several years to come.
Non-Obvious, Post-Traumatic, Life-Threatening Bleeding in Two Elderly Patients
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- 2017
Two cases are described in which inaccurate diagnoses lead to inadequate treatment of major bleeding in patients receiving anticoagulant therapy.
Practical issues with vitamin K antagonists: elevated INRs, low time-in-therapeutic range, and warfarin failure
- MedicineJournal of Thrombosis and Thrombolysis
- 2011
An overview of the most commonly used vitamin K antagonists is provided and the importance of assessing quality of anticoagulation with respect to clinical outcomes is discussed, drawing on evidence where applicable and expert opinion where evidence is limited.
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Premarketing studies are ongoing on new antidotes (idarucizumab, andexanet, aripazine), which appear to be suitable for the treatment of DOAC-induced life-threatening hemorrhage, which may partly neutralize low-molecular-weight heparins.
Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy.
- MedicineWorld journal of gastroenterology
- 2013
Intrahepatic hemorrhage is a very rare complication of warfarin, and an 18-year-old woman with antiphospholipid syndrome experienced intra hepatic and subgaleal hemorrhage although she did not have any risk factors for bleeding or instability of the international normalized ratio control.
New oral anticoagulants: how safe are they?
- Medicine
- 2016
This article has compared warfarin with the commonly used new oral anticoagulants to determine whether their use is safe in Sri Lanka.
Anti-coagulation Drug Warfarin Contributes to Severe Adverse Outcomes in Prolonged Unsupervised Use: A Double-edged Sword
- MedicineCureus
- 2018
A 58-year-old Caucasian male presented with non-traumatic acute quadriplegia with cord compression starting at the 3rd cervical (C3) level and continuing throughout the entire spinal cord and it became evident that his patient had been on a prolonged and unsupervised warfarin (Coumadin) regimen for congestive heart failure without primary care follow-up or routine laboratory testing.
When to stop, how to reverse, and when to restart antithrombotic drugs periendoscopically in nonvariceal upper gastrointestinal bleeding
- Medicine, Biology
- 2016
The misconceptions about warfarin.
- MedicineQJM : monthly journal of the Association of Physicians
- 2011
The role of anti-platelet agents, non-steroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors in worsening warfarin-related bleeding needs emphasis.
Diagnosis and management of the antiphospholipid syndrome
- MedicineBMJ : British Medical Journal
- 2010
This complicated and intriguing syndrome is introduced, and basic guiding principles for the recognition, diagnosis, and management of affected patients are provided.
References
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