Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging.

@article{Zhou2008PracticalDA,
  title={Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging.},
  author={Jinyuan Zhou and Jaishri O Blakeley and Jun Hua and Mina Kim and John Laterra and Martin G. Pomper and P C M van Zijl},
  journal={Magnetic resonance in medicine},
  year={2008},
  volume={60 4},
  pages={842-9}
}
Amide proton transfer (APT) imaging is a type of chemical exchange-dependent saturation transfer (CEST) magnetic resonance imaging (MRI) in which amide protons of endogenous mobile proteins and peptides in tissue are detected. Initial studies have shown promising results for distinguishing tumor from surrounding brain in patients, but these data were hampered by magnetic field inhomogeneity and a low signal-to-noise ratio (SNR). Here a practical six-offset APT data acquisition scheme is… CONTINUE READING