Practical characteristics of adaptive design in phase 2 and 3 clinical trials

@article{Sato2018PracticalCO,
  title={Practical characteristics of adaptive design in phase 2 and 3 clinical trials},
  author={A. Sato and M. Shimura and M. Gosho},
  journal={Journal of Clinical Pharmacy and Therapeutics},
  year={2018},
  volume={43},
  pages={170 - 180}
}
Adaptive design methods are expected to be ethical, reflect real medical practice, increase the likelihood of research and development success and reduce the allocation of patients into ineffective treatment groups by the early termination of clinical trials. However, the comprehensive details regarding which types of clinical trials will include adaptive designs remain unclear. We examined the practical characteristics of adaptive design used in clinical trials. 
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