Practical approach to analgesia and sedation in the neonatal intensive care unit.

@article{Menon1998PracticalAT,
  title={Practical approach to analgesia and sedation in the neonatal intensive care unit.},
  author={Gopi Menon and K. J.S. Anand and Neil McIntosh},
  journal={Seminars in perinatology},
  year={1998},
  volume={22 5},
  pages={417-24}
}
The anatomic and physiological bases for nociception are present even in very preterm neonates. Neonates show the same behavioral, endocrine, and metabolic responses to noxious stimuli as older subjects. Preterm infants appear to be more sensitive to painful stimuli and have heightened responses to successive stimuli. Infants receiving intensive care are subjected to frequent stressful procedures and also chronic noxious influences related to the environment of care. Inflammatory conditions… CONTINUE READING