Practical and analytical aspects of using friend controls in case-control studies: experience from a case-control study of childhood cancer.

@article{Bunin2011PracticalAA,
  title={Practical and analytical aspects of using friend controls in case-control studies: experience from a case-control study of childhood cancer.},
  author={Greta R. Bunin and Saran Vardhanabhuti and Agueda Lin and Greta L Anschuetz and Nandita Mitra},
  journal={Paediatric and perinatal epidemiology},
  year={2011},
  volume={25 5},
  pages={402-12}
}
We report empirical data on the use of friend controls, specifically response rates, case-control concordance and analytical approaches. The data derive from a North American multi-institutional study of childhood cancer that was conducted in 2002-07 and that focused on paternal exposures. Case parents nominated friends as potential controls; up to three controls participated per case. For 137 (69%) of the 199 case families, at least one control parent participated. Of 374 potential controls… CONTINUE READING

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