Practical Issues in the Management of Hypersensitivity Reactions: Sulfonamides

@article{Tilles2001PracticalII,
  title={Practical Issues in the Management of Hypersensitivity Reactions: Sulfonamides},
  author={Stephen A. Tilles},
  journal={Southern Medical Journal},
  year={2001},
  volume={94},
  pages={817-824}
}
  • S. Tilles
  • Published 1 August 2001
  • Medicine, Biology
  • Southern Medical Journal
Approximately 3% of the general population and 60% of patients with human immunodeficiency virus (HIV) infection have adverse reactions when treated with sulfonamide antimicrobials. The most common clinical manifestations of sulfonamide hypersensitivity are fever and a maculopapular rash 7 to 14 days after initiating therapy, though a variety of more severe manifestations may occur. The sulfonamide chemical moiety is present in many medications that are not antimicrobials, and fortunately… 
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