Power evaluation of small drug and vaccine experiments with binary outcomes.

Abstract

Power analysis based on the Fisher exact test is used to evaluate the usefulness of alternative designs for small drug and vaccine experiments with a binary, success or failure, outcome. The emphasis is on the comparison between designs with equal and unequal allocations of animals to treated and control groups having the same total sample size, and between… (More)

Topics

Cite this paper

@article{Duchateau1998PowerEO, title={Power evaluation of small drug and vaccine experiments with binary outcomes.}, author={Lucc Duchateau and Benjamin P McDermott and George Rowlands}, journal={Statistics in medicine}, year={1998}, volume={17 1}, pages={111-20} }