Power and sample size.

  title={Power and sample size.},
  author={Larry Douglas Case and Walter T. Ambrosius},
  journal={Methods in molecular biology},
In this chapter, we discuss the concept of statistical power and show how the sample size can be chosen to ensure a desired power. Power is the probability of rejecting the null hypothesis when the null hypothesis is false, that is the probability of saying there is a difference when a difference actually exists. An underpowered study does not have a sufficiently large sample size to answer the research question of interest. An overpowered study has too large a sample size and wastes resources… CONTINUE READING

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