Powder filling into hard gelatine capsules on a tamp filling machine.

@article{Podczeck1999PowderFI,
  title={Powder filling into hard gelatine capsules on a tamp filling machine.},
  author={Fridrun Podczeck and J. M. Newton},
  journal={International journal of pharmaceutics},
  year={1999},
  volume={185 2},
  pages={237-54}
}
A series of pharmaceutical excipient powders used in capsule formulations as fillers have been filled into hard gelatine capsules on a Bosch GKF-400S tamp filling machine. These machines depend on pushing pins through a powder bed so that a unit dose is transferred into a dosing disc. This dose is then ejected into the capsule body. The results indicate that the range of powders that can be filled on this type of machine exceeds that applicable to a dosator nozzle system. Filling problems due… CONTINUE READING

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