Pou5f1 protein expression and posttranslational modification during early zebrafish development.

@article{Lippok2014Pou5f1PE,
  title={Pou5f1 protein expression and posttranslational modification during early zebrafish development.},
  author={Bernadette Lippok and Sungmin Song and Wolfgang Driever},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2014},
  volume={243 3},
  pages={468-77}
}
BACKGROUND Pou5f1/Oct4 is a transcription factor essential for maintenance of pluripotency in mammals and for control of blastula and gastrula stage gene regulatory networks in zebrafish. Information on Pou5f1 protein distribution was before this study not available for zebrafish. Therefore, we generated polyclonal antibodies that selectively recognize Pou5f1 and analyzed its protein distribution and modification during development. RESULTS Pou5f1 protein is present in unfertilized oocytes… CONTINUE READING
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