Potentiation of the carotid artery occlusion reflex by a cholinergic system in the posterior hypothalamic nucleus.

@article{Brezenoff1982PotentiationOT,
  title={Potentiation of the carotid artery occlusion reflex by a cholinergic system in the posterior hypothalamic nucleus.},
  author={Henry E. Brezenoff and Kim Carney and Jerry J. Buccafusco},
  journal={Life sciences},
  year={1982},
  volume={30 4},
  pages={
          391-400
        }
}
Bilateral occlusion of the common carotid arteries of urethane-anesthetized rats evoked a pressor response of 14 +/- 1 mm Hg. Injection into the lateral cerebral ventricle of neostigmine (0.2-1.0 microgram) or physostigmine (10-15 microgram) caused a dose-dependent increase in basal blood pressure and in the magnitude of the carotid artery occlusion (CAO) pressor reflex. Neostigmine (1 microgram) and physostigmine (15 microgram) caused nearly maximal and approximately equal degrees of… CONTINUE READING