Potentiation of pentazocine conditioned place preference by tripelennamine in rats

@article{Suzuki1991PotentiationOP,
  title={Potentiation of pentazocine conditioned place preference by tripelennamine in rats},
  author={Tsutomu Suzuki and Yoshikazu Masukawa and Yoshinao Shiozaki and Miwa Misawa},
  journal={Psychopharmacology},
  year={1991},
  volume={105},
  pages={9-12}
}
The effects of tripelennamine on place preference conditioning in rats with pentazocine were investigated. Pentazocine at a dose of 2 mg/kg (IP) slightly, but not significantly, induced a place preference. Concurrent dosing of pentazocine (2 mg/kg, IP) and tripelennamine (2.5 mg/kg, SC) significantly and prominently produced a place preference, although administration of tripelennamine (2.5 mg/kg, SC) alone did not. Chronic infusion of a dopamine D1 receptor antagonist, SCH23390 (1.0 mg/kg/day… CONTINUE READING