Potentiation of ethanol via interference with calcium channels.

  title={Potentiation of ethanol via interference with calcium channels.},
  author={Stephen I. Deutsch and M Kaushik and J A Huntzinger and M R Novitzki and J. A. Mastropaolo},
  journal={Pharmacology, biochemistry, and behavior},
  volume={38 3},
The relevance of ethanol's ability to inhibit voltage-gated and receptor-gated calcium ion conductance in vitro to its acute effects in intact animals was examined. Specifically, nimodipine (a voltage-sensitive calcium antagonist of the dihydropyridine class), indole-2-carboxylic acid (a competitive antagonist of the strychnine-insensitive glycine binding… CONTINUE READING