Potentiation of Amphetamine-induced Arousal by Starvation

@article{Campbell1971PotentiationOA,
  title={Potentiation of Amphetamine-induced Arousal by Starvation},
  author={Byron A. Campbell and H. Christian Fibiger},
  journal={Nature},
  year={1971},
  volume={233},
  pages={424-425}
}
STARVATION and amphetamine both increase behavioural arousal, and have been postulated to act through adrenergic mechanisms in the brain stem. Amphetamine is believed to induce psychomotor excitation by releasing brain catecholamines, blocking their re-uptake from the synapse and mildly inhibiting the action of the catabolizing enzyme, monoamine oxidase1–3. The drug also accelerates the turnover of nor-adrenaline in the brain stem reticular formation4. Food deprivation increases… CONTINUE READING

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