Potentiation by vitamin A of the action of anticancer agents against murine tumors.

@article{Nakagawa1985PotentiationBV,
  title={Potentiation by vitamin A of the action of anticancer agents against murine tumors.},
  author={M. Nakagawa and T. Yamaguchi and H. Ueda and N. Shiraishi and S. Komiyama and S. Akiyama and J. Ogata and M. Kuwano},
  journal={Japanese journal of cancer research : Gann},
  year={1985},
  volume={76 9},
  pages={
          887-94
        }
}
  • M. Nakagawa, T. Yamaguchi, +5 authors M. Kuwano
  • Published 1985
  • Biology, Medicine
  • Japanese journal of cancer research : Gann
  • Combinations of retinol palmitate (RP) and six different anticancer agents were examined to determine their effects on the life-span of mice bearing ascites sarcoma 180 or P388 leukemia. With ascites sarcoma 180, administration of a fixed dose of RP (3.3 mg/kg) considerably enhanced the antitumor effects of 5-fluorouracil (5-FU) (5 mg/kg, or 20 mg/kg), methotrexate (MTX) (0.5 mg/kg, or 1 mg/kg) and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) (12.5 mg/kg… CONTINUE READING

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