Potentiation by the lithium ion of morphogenetic responses to a Xenopus inducing factor.

@article{Cooke1989PotentiationBT,
  title={Potentiation by the lithium ion of morphogenetic responses to a Xenopus inducing factor.},
  author={Jonathan Cooke and Karen Symes and Eugene J. Smith},
  journal={Development},
  year={1989},
  volume={105 3},
  pages={549-58}
}
We have cultured explants of Xenopus blastular animal cap tissue from embryos that had received an earlier treatment with LiCl and from their untreated siblings, in various concentrations of XTC-cell-derived mesoderm-inducing factor (XTC-MIF, Smith, 1987; Smith et al. 1988). The pretreatment with lithium that we used transforms later morphogenesis in the whole embryo to give radialized body forms with anterior/dorsal levels of structure grossly over-represented. In addition, animal caps from… CONTINUE READING
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