Potentially fatal interaction between colchicine and disulfiram.

Goutyarthritis is a commonrheumatic complicationamongalcoholics. Colchicine is frequentlyprescribedunder this circumstance toprevent and treat episodes of gout. However, colchicine has a narrow benefit-totoxicity margin, and overdose can result in multisystem diseases (Naidus et al., 1977; Arroyo et al., 2004). Some reports indicate drugs interacting with… (More)