Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates.

@article{Jones2004PotentialUO,
  title={Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates.},
  author={Ronald N. Jones and Gary J Moet and H{\'e}lio S. Sader and Thomas R. Fritsche},
  journal={The Journal of antimicrobial chemotherapy},
  year={2004},
  volume={53 5},
  pages={804-7}
}
OBJECTIVES To evaluate the potency of a novel peptide deformylase inhibitor, NVP PDF-713, against Gram-positive organisms having resistances to linezolid or quinupristin/dalfopristin. MATERIALS AND METHODS A total of 45 strains from three genera (six species groups) were tested by reference broth microdilution methods. The mechanism of resistance to the… CONTINUE READING