Potential use of procalcitonin as a diagnostic criterion in febrile neutropenia: experience from a multicentre study.

@article{Giamarellou2004PotentialUO,
  title={Potential use of procalcitonin as a diagnostic criterion in febrile neutropenia: experience from a multicentre study.},
  author={Helen Giamarellou and Evangelos J. Giamarellos-Bourboulis and Panagiotis Repoussis and Labrini Galani and Nick Anagnostopoulos and Paraskevi Grecka and D Lubos and Mickael Aoun and Kalomoira Athanassiou and E. Fernandez Bouza and E Devigili and Vladim{\'i}r Kr{\vc}m{\'e}ry and Francesco Menichetti and E Panaretou and Evangelia Papageorgiou and Diamantis Plachouras},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2004},
  volume={10 7},
  pages={
          628-33
        }
}
In order to assess the diagnostic value of procalcitonin, 158 patients with febrile neutropenia from centres across Europe were studied. Patients with fever were diagnosed on the basis of either: (1) clinical, radiological and microbiological criteria; or (2) the procalcitonin value. In the latter case, concentrations of 0.5-1.0 ng/mL were considered diagnostic of localised infection, concentrations of 1.0-5.0 ng/mL of bacteraemia, and concentrations of > 5.0 ng/mL of severe sepsis… CONTINUE READING

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