Potential use of dendritic cells for anti-atherosclerotic therapy.

  title={Potential use of dendritic cells for anti-atherosclerotic therapy.},
  author={Ilse Van Brussel and Dorien M. Schrijvers and Emily A. Van Vr{\'e} and Hidde Bult},
  journal={Current pharmaceutical design},
  volume={19 33},
The chronic inflammatory nature of atherosclerosis is nowadays widely accepted. Dendritic cells (DCs) are likely to play a crucial role in directing innate and adaptive immunity against altered (self-)antigens, such as oxidized low density lipoproteins (oxLDL). DCs are found in early lesions and their numbers become even higher when the lesion progresses. DCs are most abundant in areas of neovascularization where they are often found near T cells. All stages from precursors to fully mature DCs… CONTINUE READING