Potential use of G protein-coupled receptor-blocking monoclonal antibodies as therapeutic agents for cancers.

  • Deron R Herr
  • Published 2012 in
    International review of cell and molecular…

Abstract

The therapeutic use of monoclonal antibodies (mAbs) is the fastest growing area of pharmaceutical development and has enjoyed significant clinical success since approval of the first mAb drug in1984. However, despite significant effort, there are still no approved therapeutic mAbs directed against the largest and most attractive family of drug targets: G… (More)
DOI: 10.1016/B978-0-12-394308-8.00002-9

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