Potential tumor- or organ-imaging agents. 27. Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols.

Abstract

A series of glyceryl 1,3-bis- and 1,2,3-tris[omega-(3-amino-2,4,6-triiodophenyl)alkanoates] were synthesized, radioiodinated with iodine-125, and evaluated for their ability to selectively localize in the liver for potential use as hepatographic imaging agents. Of the nine target compounds synthesized and evaluated in rats, glyceryl 1,2,3-tris[3-(3-amino-2… (More)

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@article{Weichert1986PotentialTO, title={Potential tumor- or organ-imaging agents. 27. Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols.}, author={Jan Weichert and Michael P. Groziak and Marc A. Longino and Susan W. Schwendner and Raymond E. Counsell}, journal={Journal of medicinal chemistry}, year={1986}, volume={29 12}, pages={2457-65} }