Potential toxicity from prolonged anesthesia: a case report of a thirty-hour anesthetic.

  title={Potential toxicity from prolonged anesthesia: a case report of a thirty-hour anesthetic.},
  author={C. Hogue and D. Perese and C. Vacanti and T. Alston},
  journal={Journal of clinical anesthesia},
  volume={2 3},
  • C. Hogue, D. Perese, +1 author T. Alston
  • Published 1990
  • Medicine
  • Journal of clinical anesthesia
  • Selection of anesthetics for prolonged administration must include consideration of potential toxicity resulting from extended exposure. This report deals with a patient undergoing a 30-hour anesthetic that included nitrous oxide (N2O) and isoflurane (9.7 MAC-hours). Serial serum inorganic fluoride levels obtained in the perioperative period demonstrated a peak fluoride level of 12.6 mumols occurring 27 hours after isoflurane was discontinued. Although higher than previously reported fluoride… CONTINUE READING
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