Potential therapeutic targets for intracerebral hemorrhage-associated inflammation: An update

@article{Ren2020PotentialTT,
  title={Potential therapeutic targets for intracerebral hemorrhage-associated inflammation: An update},
  author={Honglei Ren and Ranran Han and Xue-mei Chen and X. Liu and Jieru Wan and L. Wang and Xiuli Yang and J. Wang},
  journal={Journal of Cerebral Blood Flow & Metabolism},
  year={2020},
  volume={40},
  pages={1752 - 1768}
}
  • Honglei Ren, Ranran Han, +5 authors J. Wang
  • Published 2020
  • Biology, Medicine
  • Journal of Cerebral Blood Flow & Metabolism
  • Intracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and disability but no specific or effective treatment. In the last two decades, much has been learned about the pathologic mechanisms of ICH. It is now known that after ICH onset, immune and inflammatory responses contribute to blood–brain barrier disruption, edema development, and cell death processes, jointly resulting in secondary brain injury. However, the translation of potential therapies from preclinical to… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 155 REFERENCES
    Inflammation after Intracerebral Hemorrhage
    • 472
    Preclinical and clinical research on inflammation after intracerebral hemorrhage
    • 349
    • Highly Influential
    Intracerebral haemorrhage: mechanisms of injury and therapeutic targets
    • 569
    • PDF
    Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
    • 1,732
    • PDF
    Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation
    • 273
    Pyroptosis: host cell death and inflammation
    • 1,395
    Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia
    • 1,188
    Activation and regulation of the inflammasomes
    • 1,620