Potential therapeutic application of chondroitin sulfate/dermatan sulfate.

  title={Potential therapeutic application of chondroitin sulfate/dermatan sulfate.},
  author={Shuhei Yamada and Kazuyuki Sugahara},
  journal={Current drug discovery technologies},
  volume={5 4},
Glycosaminoglycans (GAGs) are complex polysaccharides, which play important roles in cell growth, differentiation, morphogenesis, cell migration, and bacterial/viral infections. Major GAGs include heparin (Hep)/heparan sulfate, and chondroitin sulfate (CS)/dermatan sulfate (DS). Hep has been used for the treatment of thromboembolic disorders for more than 75 years, and has an established position in therapy today. CS/DS has attracted less attention and its clinical use is limited. However, CS… CONTINUE READING


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