Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

@article{Li2006PotentialTG,
  title={Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.},
  author={Hao Li and Kathie M Bishop and D D O'leary},
  journal={Molecular and cellular neurosciences},
  year={2006},
  volume={33 2},
  pages={136-49}
}
EMX2 and PAX6 are expressed by cortical progenitors and specify area patterning. We used representational difference analysis (RDA) to compare expressed RNAs from wild type and Emx2-/- cortex and identified 41 unique clones. Using secondary screening by in situ hybridization, we selected five genes for further analysis, Cdk4, Cofilin1, Crmp1, ME2, and Odz4, involved in neuronal proliferation, differentiation, migration, and axon guidance. Each exhibits differential expression in wild type… CONTINUE READING
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