Potential significance of EMP3 in patients with upper urinary tract urothelial carcinoma: crosstalk with ErbB2-PI3K-Akt pathway.

@article{Wang2014PotentialSO,
  title={Potential significance of EMP3 in patients with upper urinary tract urothelial carcinoma: crosstalk with ErbB2-PI3K-Akt pathway.},
  author={Yi-wen Wang and Wei-ming Li and W J Wu and C Y Chai and Hsiao-Sheng Liu and M D Lai and N. H. Chow},
  journal={The Journal of urology},
  year={2014},
  volume={192 1},
  pages={242-51}
}
PURPOSE Upper urinary tract (pyelocalyceal cavities and ureter) urothelial carcinoma is a relatively rare neoplastic disease. Although diagnosis and treatment of this tumor variant have improved significantly, accurate risk stratification remains a challenge. To identify the putative oncogene involved in urothelial carcinoma progression we performed bioinformatics guided experimental investigation targeting chromosome 19q13. MATERIALS AND METHODS We investigated the effects of EMP3 on cancer… CONTINUE READING
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