Potential roles of antisense technology in cancer chemotherapy

Abstract

Antisense technology may play a major role in cancer chemotherapy. It is clearly a tool of exceptional value in the functionalization of genes and their validation as potential targets for cancer chemotherapy. Additionally, there is now substantial evidence that antisense drugs are safe, and a growing body of data showing activity in animal models of human disease including cancer, and suggesting efficacy in patients with cancer. In this article, I review the progress in the technology, the anticancer antisense drugs in development and potential roles that antisense technology might play.

DOI: 10.1038/sj.onc.1204093

Cite this paper

@article{Crooke2000PotentialRO, title={Potential roles of antisense technology in cancer chemotherapy}, author={Stanley T . Crooke}, journal={Oncogene}, year={2000}, volume={19}, pages={6651-6659} }