Potential role of the NK1 receptor antagonists in chemotherapy-induced nausea and vomiting

@article{Hesketh2000PotentialRO,
  title={Potential role of the NK1 receptor antagonists in chemotherapy-induced nausea and vomiting},
  author={P. Hesketh},
  journal={Supportive Care in Cancer},
  year={2000},
  volume={9},
  pages={350-354}
}
  • P. Hesketh
  • Published 2000
  • Medicine
  • Supportive Care in Cancer
Abstract. Better tolerated and more effective means of controlling chemotherapy-induced nausea and vomiting have been introduced over the past decade. Despite the progress made, incompletely controlled emesis is a persistent problem for significant numbers of patients receiving chemotherapy. Efforts to improve antiemetic control further are ongoing. The most interesting new class of antiemetics under development focuses on antagonism of the neurotransmitter substance P. Substance P exerts its… Expand

Paper Mentions

Interventional Clinical Trial
The aim of the study is to compare efficacy and tolerability of aprepitant plus dexamethasone versus metoclopramide plus dexamethasone in the prevention of cisplatin-induced delayed… Expand
ConditionsEmesis
InterventionDrug
New treatment options for chemotherapy-induced nausea and vomiting
Cost-effectiveness of antiemetics use during cancer chemotherapy
Treatment of Chemotherapy-Induced Nausea and Vomiting
New antiemetic drugs.
  • F. Roila, S. Fatigoni
  • Medicine
  • Annals of oncology : official journal of the European Society for Medical Oncology
  • 2006
Management of chemotherapy induced emesis
Differential clinical pharmacology of rolapitant in delayed chemotherapy-induced nausea and vomiting (CINV)
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