Potential role of phospholipases in virulence and fungal pathogenesis.

  title={Potential role of phospholipases in virulence and fungal pathogenesis.},
  author={Mahmoud Afif Ghannoum},
  journal={Clinical microbiology reviews},
  volume={13 1},
  pages={122-43, table of contents}
Microbial pathogens use a number of genetic strategies to invade the host and cause infection. These common themes are found throughout microbial systems. Secretion of enzymes, such as phospholipase, has been proposed as one of these themes that are used by bacteria, parasites, and pathogenic fungi. The role of extracellular phospholipase as a potential virulence factor in pathogenic fungi, including Candida albicans, Cryptococcus neoformans, and Aspergillus, has gained credence recently. In… CONTINUE READING
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