Potential role of micro-RNAs in head and neck tumorigenesis.

  title={Potential role of micro-RNAs in head and neck tumorigenesis.},
  author={Nham Tran and Christopher J O'brien and Jonathan Owen Clark and Barbara R. Rose},
  journal={Head & neck},
  volume={32 8},
A new class of regulatory molecules known as microRNAs (miRNAs) is redefining our understanding of the molecular pathways associated with tumorigenesis. These miRNAs are small noncoding RNA (ncRNA) sequences with potent regulatory potential. The aberrant expression of miRNAs has been associated with the development of various tumors. It has been suggested that miRNAs can both regulate and act as tumor-suppressor genes and oncogenes. Our understanding of the role of miRNAs in head and neck… CONTINUE READING
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